ventrículo e do canal ependimário, havendo formação da siringomielia. Assim, para este autor, a siringomielia, a malformação de Arnold-Chiari, os cistos do. FISIOPATOLOGIA .. vasculite de pequeno, médio e grande calibre e linfáticas), de origem neuropática (diabetes, hanseníase, tabes dorsalis e siringomielia). de malformação de Chiari I, ou na área afetada pela siringomielia Ercis et Ainda não está perfeitamente definida a fisiopatologia exata da dermatite.

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Siringomielia: fisiopatologia e tratamento.

Antiphospholipid syndrome is an acquired multisystem disorder characterized by recurrent thromboses in the arterial system, venous system, or both. Antiphospholipid syndrome is classified into 2 groups: Secondary antiphospholipid syndrome is often associated with systemic lupus erythematosus and less frequently with infections, drugs and other diseases.

Serologic markers are antiphospholipid antibodies, lupus anticoagulant and anticardiolipin. The primary diagnostic criteria include arterial thrombosis or venous thrombosis and recurrent fetal loss. Cutaneous manifestations include livedo reticularis, cutaneous ulceration and livedo vasculitis. The mainstays of prophylaxis and treatment of thrombosis are anticoagulant and antiplatelet agents.

Skin manifestations; Antiphospholipid syndrome; Thrombosis. Em Bowie et al. Em Harris et al. The systemic nature of antiphospholipid syndrome. Antiphospholipid syndrome and the skin.

J Am Acad Dermatol. Eine serodiagnostichereaktion bey syphilis. A new serologically active phospholipid from beef heart. A hemorrhagic disorder caused by circulating anticoagulant in patients with disseminated lupus erythematosus.

Siringomielia : National Institute of Neurological Disorders and Stroke (NINDS)

Thrombosis in systemic lupus erythematosus despite circulating antibodies. Acquired Inhibitors of blood coagulation. Intrauterine death and circulating anticoagulant “antithromboplastin”. Anticardiolipin antibodies ACA directed not to cardiolipin but to a plasma protein cofactor. Anti-phospholipid antibodies are direct against a complex antigen that includes a lipid-binding inhibitor of coagulation: Lupus anticoagulants are stronger risk factors for thrombosis then anticardiolipin antibodies in the antiphospholipid syndrome: Thrombotic syndromes and auto immunes diseases.


Rheum Dis Clin North Am. Anti-prothrombin antibodies as a potential risk factor of recurrent venous thromboembolism. Heart valve involvement Libman-Sacks endocarditis in the antiphospholipid syndrome. High impact of antiphospholipid syndrome on irreversible organ damage and survival of patients with systemic lupus erythematosus. Management of the obstetric antiphospholipid siribgomielia. Antiphospholipid antibodies and the antiphospholipid antibody syndrome.

A family study of anticardiolipin antibodies and associated clinical conditions. The immunogenetics of the antiphospholipid syndrome, anticardiolipin antibodies, and lupus anticoagulant.

Immunology and clinical importance of antiphospholipid antibodies. Pathogenesis and treatment of the antiphospholipid antibody syndrome. Med Clin North Am.

Salmon JE, Girrardi G. The role of complement in the antiphospholipid syndrome. Activation of cultured vascular endothelial cells by antiphospholipid antibodies. Value of IgA anticariolipin and anti-beta 2-glycoprotein I antibody testing in patients with pregnancy morbidity.

Rheum Dis Clin North. Antiphospholipid Hughes syndrome in systemic lupus erythematosus. N Engl J Med. Cutaneous manifestations associated with antiphospholipid antibodies.

Cutaneous thrombosis, cerebrovascular thrombosis and lupus anticoagulant- the Sneddon syndrome. Report of 10 cases. Dermatologic aspects of antiphospholipid syndrome. Antiphospholipid antibodies and thrombosis. Antiprothrombin antibodies and the diagnosis of antiphospholipid syndrome. Myers B, Gould J. The place of beta 2 glycoprotein 1 in the assessment of antiphospholipid syndrome.

Testing for and clinical significance of anticardiolipin antibodies. Clin Diagn Lab Immunol. Clinical significance of anticardiolipin and anti-beta 2-glycoprotein antibodies. Int Arch Allergy Immunol. Diagnosis and management of patients with the antiphospholipid syndrome. Thrombosis and antithrombotic therapy.


The catastrophic antiphospholipid Asherson’s syndrome in a review. Correlation between lupus flsiopatologia and anticardiolipin antibodies in patients with prolongated activated partial thrombo plastin times. Loskshin MD, Erkan D.

Seborrheic dermatitis

Treatment of the antiphospholipid syndrome. Update on the antiphospholipid syndrome. Lassere M, Empson M.

Treatment of antiphospholipid syndrome in pregnants-a systematic review of randomized therapeutic trial. The fisiopatoloyia of thrombosis in the antiphospholipid-antibody syndrome. M, Denburg J, Hirsh J, et al. A comparison of two intensities of warfarin for the prevention of recurrent thrombosis in patients with the antiphospholipid antibody syndrome. Crowther M, Wisloff F.

Evidence based treatment of the antiphospholipid syn drome. Optimal anticoagulant therapy for thrombosis.

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Prognostic factors and clustering of serious clinical outcomes in antiphospholipid syndrome. Anticardiolipin syndrome with only skin envolvement. Natural history and risk factors for thrombosis in patients with antiphospholipid antibodies: Clinical and analytical manifestations of primary antiphospholipid antibody syndrome. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Services on Demand Journal. Marque a resposta correta: Quanto ao uso de anticoagulantes na gravidez: No tratamento da trombose na SAF: Rio Branco, 39 How to cite this article.